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Medical Disclaimer

This app is a tracking and observation tool only. It is not a substitute for professional medical advice. Always consult with your GP, pediatrician, or healthcare provider regarding sleep issues and medication management. All medical decisions should be made in consultation with qualified healthcare professionals.

Second-Line Medications

When behavioral strategies and melatonin are not sufficient, specialists may consider other medications. These are typically used only under the supervision of a consultant paediatrician or child psychiatrist.

⚠️ Expert Guidance Required

The use of these medications for sleep in children is often "off-license", meaning the manufacturer hasn't specifically applied for a license for this use in children. This is common in paediatrics, but requires careful specialist monitoring and shared care agreements.

Clonidine

Alpha-2 adrenergic agonist

Main Use

Sleep onset and maintenance, often with ADHD

Common Side Effects

Dry mouth, drowsiness, low blood pressure, headache. IMPORTANT: Never stop abruptly as this can cause a rapid increase in blood pressure (rebound hypertension).

View Official BNFC Information ↗

Promethazine (Phenergan)

Sedating Antihistamine

Main Use

Short-term sleep onset help

Common Side Effects

Morning drowsiness, blurred vision, dry mouth, constipation

View Official BNFC Information ↗

Alimemazine (Vallergan)

Sedating Antihistamine

Main Use

Severe sleep disturbances in children

Common Side Effects

Drowsiness, dry mouth, thickening of mucus, coordination issues

View Official BNFC Information ↗

Chloral Hydrate

Sedative-hypnotic / CNS depressant

Main Use

Short-term treatment (max 2 weeks) for severe insomnia specifically in neurodevelopmental disorders

Common Side Effects

Drowsiness (can last 24h), stomach irritation, nausea, paradoxical excitement. Very strict monitoring required.

View Official BNFC Information ↗

What to Track

If your child is starting a second-line medication, it is vital to keep detailed logs to help your specialist assess the benefit vs potential side effects:

  • Onset: How quickly do they fall asleep?
  • Maintenance: How many times do they wake? How long for?
  • Daytime Effects: Do they seem drowsy, irritable, or "hungover" the next day?
  • Vital Signs: Some medications (like Clonidine) may require periodic blood pressure checks.

⚠️ Critical Medical Disclaimer

Always consult with your GP or specialist paediatrician before starting, stopping, or changing any medication. Every child's medical history is unique, and these medications interact with other conditions and treatments in complex ways.